ANTIMICROBIAL ACTIVITY FROM LEAVES AND STEMS OF TRIPHASIA TRIFOLIA (BURM. F.) P. WILSON
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Abstract
Air dried leaves and stems of Triphasia trifolia were macerated with hexane, dichloromethane and ethanol, respectively. Preliminary chemical screening results of these crude extracts from its leaves and stems found alkaloids, flavonoids, tannins and triterpenoids. Antimicrobial activity of the crude extracts was tested by agar diffusion method. Tetracycline was used as a positive control. The crude ethanolic extract from its stems showed the strongest antimicrobial activity against both gram positive (S. aureus, S. epidermidis, B. subtilis and M. luteus) and gram negative bacteria (E. coli) while the crude dichloromethane and ethanolic extracts from its leaves showed strong inhibition of B. subtilis and M. luteus. In conclusion, the crude ethanolic extract from the stems of T. trifolia exhibit strong antimicrobial activity. Therefore, it might be used for potential source for novel antimicrobial drugs in the future.
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