EVALUATION OF ANTIMICROBIAL, ANTIOXIDANT AND CYTOTOXIC POTENTIALS OF TREE KARL PHIT REMEDY
Article Sidebar
Main Article Content
Abstract
Tree Karl Phit is a traditional Thai medicine remedy used as an antipyretic, anti-inflammatory and health tonic remedy. It consists of the dried rhizomes of Boesenbergia rotunda (L.) Mansf., Alpinia galanga (L.) Sw. and dried roots of Ocimum tenuiflorum L. in an equal weight. The ethanolic extract of the remedy demonstrated strong inhibitory potential against gram positive bacteria, moderate to weak potential against fungi and no activity against gram-negative bacteria. DPPH scavenging activity of the remedy showed its antioxidant potential. The remedy was found to be non-cytotoxic by brine shrimp lethality assay.
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Journal of TCI is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence, unless otherwise stated. Please read our Policies page for more information.
References
Bell SC, Grundy WE. 1968. Preparation of agar wells for antibiotic assay. Appl Microbiol. 16 (10): 1611-1612.
Brand-Williams W, Cuvelier ME, Berset C. 1995. Use of a free radical method to evaluate antioxidant activity. Lebensm Wiss Technol 28(1): 25-30.
Carballo JL, Hernández-Inda ZL, Pérez P, García-Grávalos MD. 2002. A comparison between two brine shrimp assays to detect in vitro cytotoxicity in marine natural products. BMC Biotechnol 2: 17.
Chan EWC, Lim YY, Wong LF, Lianto FS, Wong SK, Lim KK, Joe CE, Lim TY. 2008. Antioxidant and tyrosinase inhibition properties of leaves and rhizomes of ginger species. Food Chem. 109: 477–483.
Clinical and Laboratory Standards Institute. 2006. M7 - A7. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically; approved standard, 7th ed. Clinical and Laboratory Standards Institute, Wayne, PA.
Holetz FB, Pessini GL, Sanches NR, Cortez DAG, Nakamura CV, Filho BPD. 2002. Screening of some plants used in the Brazilian folk medicine for the treatment of infectious diseases. Mem Inst Oswaldo Cruz. 97: 1027–1031.
Kamonwannasit S, Nantapong N, Kumkrai P, Luecha P, Kupittayanant S, Chudapongse N. 2013. Antibacterial activity of Aquilaria crassna leaf extract against Staphylococcus epidermidis by disruption of cell wall. Ann. Clin. Microbiol. Antimicrob. 12:20. Available from http://www.ann-clinmicrob.com/content/12/1/20.
Meyer BN, Ferrigni NR, Putnam JE, Jacobsen LB, Nichols DE, McLaughlin JL. 1982. Brine shrimp: A convenient general bioassay for active plant constituents. J. Med. Plant. Res. 45: 31 -34.
Subcharoen P. 2007. History, Evaluation and Application of Thai Traditional Medicine. Bangkok: Samcharoenpanich Publisher Ltd.
Rukayadi Y, Lau KY, Zainin NS, Zakaria M, Abas F. 2013. Screening antimicrobial activity of tropical edible medicinal plant extracts against five standard microorganisms for natural food preservative. Int. Food Res. J. 20(5): 2905-2910.
Samie A, Obi CL, Bessong PO, Namrita L. 2005. Activity profiles of fourteen selected medicinal plants from Rural Venda communities in South Africa against fifteen clinical bacterial species. Afr. J. Biotechnol. 4 (12): 1443-1451.
Visweswara Rao P, Sujana P, Vijaykanth T, Sankar NS, Vijaya Kumar B, Naidu D, Gan SH. 2013. Analysis of the phytochemical content and the antibacterial, antifungal and antioxidant activities of the roots, stems and leaves of Hemidesmus indicus, Ocimum sanctum and Tinospora cordifolia. Int. J. Pharmacol. 9 (5): 277-287.
World Health Organization. 2013. WHO traditional medicine strategy: 2014-2023. Switzerland: WHO Press. [cited 2014 March 26]. Available from http://www.who.int/medicines/publications/traditional/trm_strategy14_23/en/.