Effects of Warfarin Nomogram in initial phase warfarin patients at Charoenkrung Pracharak hospital

2024-01-19T13:31:29+07:00

Most physicians initiate and adjust warfarin dose based on International Normalized Ratio (INR)and their clinical judgment. This study was conducted to investigate the effects of using warfarin nomograms in patients initiated warfarin at Charoenkrung Pracharak hospital. This study was a randomized controlled trial involving patients who started using warfarin while hospitalized at Charoenkrung Pracharak hospital from August to November 2023. The experimental group received the initiation and dosage adjustments of warfarin using the warfarin nomograms, while the control group had their warfarin initiation and dosage adjustments based on the physician's clinical judgment, analyzing the proportion of patients who achieved an INR between 2.0 and 3.0 within 14 days after warfarin initiation. From a total sample of 98 individuals, divided into control (49) and experimental (49) groups, Baseline characteristics of both groups were not significantly different except for gender. The research findings indicated a statistically significant difference between the experimental and control groups concerning the proportion of patients with INR values within the range of 2.0 to 3.0 within 14 days after receiving warfarin (44.9% and 24.5%, respectively, p=0.034). The use of warfarin nomograms for initiating and adjusting dosages allows patients to achieve their target INR range more effectively than starting and adjusting doses solely based on physician judgment. Additionally, the safety of using warfarin nomograms does not significantly differ from initiating and adjusting doses solely based on physician judgment.

Evaluating Pharmacy Students' Perceptions with Outcome-Based Learning in Toxicology Testing

2024-01-18T12:33:12+07:00

This research marks the inaugural exploration into student perceptions of outcome-based learning at Rangsit University's College of Pharmacy. The study focuses on PHA 552 Toxicology Testing, a novel lecture course in the industrial pharmacy curriculum, offering one credit to fifth-year students. Currently, the curriculum is content-centric, but a shift towards outcome-based learning is anticipated. The course serves as a pilot for innovative educational methods, employing a constructivist alignment strategy. This approach used intended learning outcomes to guide the creation of relevant assessments and teaching activities, based on the ADDIE model. The objective was to devise teaching strategies using the ADDIE framework and assess student reactions to outcome-based learning in this context. In this study, an online questionnaire served as the primary instrument for collecting pharmacy students' perspectives on the outcome-based learning of this course. The assessment of the learning approach's effectiveness was determined through a descriptive analysis of the average scores for each survey question. Feedback from 76 students revealed that the ADDIE model successfully guided the comprehensive analysis, design, development, implementation, and evaluation of learning activities, all aligned with set outcomes. Activities were thoughtfully designed using a backward design, ensuring alignment with these outcomes. Students responded positively to the course process, teaching methods, and evaluation, particularly appreciating the formative assessments and the clarity of evaluation methods. However, course timing was a noted concern. Overall, the ADDIE model's application in creating the PHA 552 course proved effective, with most students indicating high satisfaction with the outcome-based approach.

Interprofessional Journal of Health Sciences

Effects of Warfarin Nomogram in initial phase warfarin patients at Charoenkrung Pracharak hospital

Evaluating Pharmacy Students' Perceptions with Outcome-Based Learning in Toxicology Testing